Does pH of tyrode solution modify glucose and electrolyte jejunal absorption in rats?

Does pH of tyrode solution modify glucose and electrolyte jejunal absorption in rats?

Studies have shown that glucose is able to decrease the pH of the surface epithelium jejunal preparations when added in vitro and the existence of a high concentration of protons in the immediate area of the mucosa could be of considerable significance for absorption of electrolytes. The aim of this study is to assess whether the change in pH of Tyrode (solution used for perfusion of the jejunu...

Is oral rice electrolyte solution superior to glucose electrolyte solution in infantile diarrhoea?

Jejunal water and electrolyte absorption from two proprietary enteral feeds in man: importance of sodium content.

Jejunostomy losses of Na+ and water during enteral nutrition after massive intestinal resection may be severe. We have attempted to analyse this practical problem by using an in vivo perfusion technique in healthy volunteers to study Na+, water and nutrient absorption from a short (25 cm) segment of jejunum during perfusion of an isotonic solution of the elemental diet Vivonex. Further solution...

Increased Jejunal Absorption of Glucose in Rats Submitted to Blockade of GABAA Receptors in the Hypothalamic Paraventricular Nucleus

In this study we investigated the status of jejunal absorption and peripheral metabolism of glucose following disinhibition of paraventricular nucleus (PVN) induced by the GABAA antagonist bicuculline methiodide (BMI). Adult male Wistar rats (270-300g) were anesthetized to implant unilateral guide cannula targeted to PVN for later microinjection of BMI (10 pmol/100 nl, n=6) or vehicle (NaCl 0.9...

Altered jejunal surface pH in coeliac disease: its effect on propranolol and folic acid absorption.

1. Propranolol and folic acid absorption were studied separately in healthy subjects, non-coeliac patients and patients with treated and untreated coeliac disease. 2. The surface pH of jejunal biopsy samples was measured with a pH electrode. 3. When compared with values found in healthy subjects, plasma propranolol levels were elevated in coeliac disease and, in contrast, serum folic acid level...